OptygenHP - New for 2017

OptygenHP - New for 2017

Clinically Proven to Improve Performance

120 Capsules

This new OPTYGEN-HP delivers the levels of nutrients that have been shown in the most recent clinical research to improve oxygen utilization, reduce lactic acid and allow the body to adapt to high levels of physical stress. 

 New & Improved
 The Most Powerful Optygen-HP formula available
 Now with Cordyceps Militaris and Cordyceps Sinensis


In stock

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Detailed Information

The new and improved OPTYGENHP has been engineered to optimize performance for endurance athletes and is the best OPTYGEN formula we’ve ever developed.

This next-generation OPTYGENHP has been upgraded with the most potent blend of Cordyceps mushroom available to maximize your VO2max and time to exhaustion. In addition, there’s a clinically effective dose of premium grade Rhodiola because the latest clinical research shows the combination of these two endurance-specific adaptogens improves aerobic performance. 

Each serving also delivers 1500mg of Beta-Alanine to boosts strength and enhance exercise capacity so you can exercise longer.


  1. A difference maker during the season Review by Hoeferland

    I've been a long time user of Optygen and during the past season have used OptygenHP from March through August with great results. What I notice the most is the ability to push harder later in races with less lactic build up, and my recovery between races and workouts is much, much better. A great product that really helps you be your best during your events and maximize the time between. (Posted on 10/11/2017)

  2. Makes the Intense Training Blocks Easier Review by Will

    When I am using Optygen I notice that I am able to sustain a higher training volume for longer and ultimately reach a higher peak fitness. Seems to work perfectly for both endurance blocks and super intense blocks based around short course racing. (Posted on 9/26/2017)

  3. Awesome! Review by Andrew

    The best way to really feel the benefits, are to use this product and then stop. You'll struggle in hill workouts you once mastered. Long runs will feel even longer, and simple recovery runs will feel harder at slower paces. I'm a big believer that what you put in is what you get and I can tell a big difference in my training from when I use Optygen and Multi-V and when I am not. (Posted on 8/12/2017)

  4. The BEST keeps getting better! Review by Danielle

    Hard to describe the benefits without experiencing them yourself! Once you try OptygenHP you will wonder why you haven't tried it sooner! I so appreciate First Endurance's commitment to have the best product with up to date science to back up their formulas. I simply cannot train/race without it! (Posted on 5/5/2017)

  5. Nailed it! Review by Brad

    Some feedback on the Optygen HP Prototype, two words, nailed it!
    I've been using the prototype for a couple weeks now. I noticed it the first time I took it and thought placebo effect, but now that I keep feeling the same way workout after workout it has to be real.
    Last season, I was taking both Optygen products to get the cordyceps in addition to what HP offered. This season, I dropped original Optygen and replaced with Home Defense Cordyceps and was taking that in addition to HP. I liked the effect better than Optygen and Optygen HP. When I saw the prototype mix I was excited to try it, and I am very satisfied with the results.
    I'm an IM FMOP age grouper (45-50 this year) and have a coach. Last week's long run (14 miles) felt like a walk at 8:11 pace, when my usual long run pace is 8:30. HR at 8:11 was 8 beats per min lower than usual 8:30 runs. Additionally, my coach upped my track interval paces from max 7min/mile to 6:40 (he doesn't know I take this stuff, but he must be noticing something in the data too). Sure, I'm getting in better shape, but I strongly believe prototype is facilitating that process nicely! (Posted on 4/19/2017)

  6. No surprises Review by Doug

    No surprised, I expected it to work, and it does! This is normal for First Endurance products. The people at First Endurance have always taken the approach of using the latest available research and building products with the customer in mind. I have been using 1st Endurance products for more than 10 years. I am thrilled to have the Cordyceps back in the formula. I had a huge training week and I was able to push myself harder every day. Time to order my next bottle! (Posted on 4/16/2017)

  7. Noticeable benefits Review by Matt B

    I'm running faster with less burn in my legs day after day. My recovery between runs is noticeably shorter too. I take the new HP in the morning and then have Ultragen after my workouts. Can now train harder and recover faster so I can do it again the next day. You get what you pay for.

    (Posted on 4/14/2017)

  8. Dietitian approved! Review by Breanne

    I have all of my clients on Optygen, many of them taking HP and the original formula. So when the prototype came out with the Rhodiola Rosea and Cordyceps,I couldn't be happier. Now we get everything we need for optimal performance and recovery in this supplement. Also, as a professional cyclist, Optygen is an essential part of my everyday needs. Science and application together, so fantastic! (Posted on 4/9/2017)

  9. The best! Review by A Phillips

    I've always been very cynical about supplements. A guy I race with told me about the new HP formula, so I figured I'd give it a try. Been using it for three weeks now and am having a blast smashing my old pr's. (Posted on 4/6/2017)

  10. The evolution continues! Review by Tbird

    I've been relentlessly pushing my body for 30+ years now on the bike and off and have tried nearly every highly-touted endurance supplement out there. First Endurance's OptygenHP is the only product that keeps me coming back year after year.
    The thing I love most about First Endurance is their "measure twice, cut once" approach. I know that any update or tweak to a formulation they make is the result of tireless review and research and this latest update to Optygen HP lives up to my expectation of that benchmark. I was excited to see Cordyceps back on the label and particularly stoked with the all-natural/vegan approach, ie, no more red capsules or gelatin.
    I've been using this new formulation for 3 weeks now and the results are right in line what I've come to expect from OptygenHP. Faster recovery between intense efforts and a noticeable "spring in my step" the day after hard workouts.
    Hat's off for raising the bar yet-again on an already stellar product! (Posted on 4/3/2017)

  11. Definite results! Review by DN

    I decided to start using the HP prototype formula. Definitely got a noticeable bump in power! Also noticed a difference with my sub-threshold intervals. This along with the Ultragen recovery drink has been HUGE! (Posted on 4/3/2017)

  12. Love this stuff Review by Amy Wagner

    This is my favorite First Endurance product. I can train harder than ever now. I definitely noticed a difference when I started taking them. I recover quicker and have more endurance on big climbs, even if there's one after another. Stuff's amazing! (Posted on 3/31/2017)

  13. Game changer! Review by Christian

    First Endurance FINALLY went back to the base HP formula that everyone loved! Gotta love that it's 100% natural now too. I notice it most during intervals. My power is better and I recover a lot faster. (Posted on 3/29/2017)

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What is the new OPTYGENHP?

This new formula is designed specifically to optimize performance for endurance athletes. OPTYGENHP delivers the levels of nutrients that have been shown in clinical research to improve oxygen utilization, reduce lactic acid and allow the body to adapt to high levels of physical stress.  

What benefits will I experience with this new OptygenHP formula?

This formulation is based on the latest human clinical research on elite endurance athletes.  The research has shown the following endurance benefits.

  • Increase in Endurance and Performance
  • Reduces Lactic Acid
  • Increase in VO2 Max
  • Increase in time-to-Exhaustion
  • Increase anaerobic threshold (AT)
  • Improves exercise capacity
  • Increase maximal oxygen uptake
  • Improves oxygen Utilization
  • Increases ATP production

Is this formula legal?

Absolutely.  All Ingredients in this formula are legal for use in Olympic events, triathlons, bicycle races, etc.  [Based on the banned substance list in the current USADA (US anti-doping association) & (WADA (World anti-doping association)]. In addition we don’t use any excipients or fillers, ensuring all of the ingredients in the product are listed on the label.

Why does OPTYGENHP contain adaptagens?

The OPTYGENHP formula utilizes two adaptagens that are the primary ingredients in the formulation.  Patented Rhodiola Rosea and Cordyceps are both found and cultivated in Tibet. Both these herbs play critical roles in allowing the body to adapt to high levels of physical stress (similar to the stress a body is subject to when climbing Everest).  It’s these adaptations to hypoxia (lack of oxygen) which led researchers to also test its effects on elite athletes.  Both Rhodiola and Cordyceps have been clinically shown to increase VO2Max, lung function, oxygen utilization and anaerobic threshold significantly.   

Why does this formula contain Beta-Alanine?

A number of clinical studies have been conducted to evaluate the effects of beta-alanine supplementation on VO2max, time to exhaustion and lactate concentrations. Subjects supplemented with beta-alanine for six weeks. The group experienced a significant increase in VO2max, an improvement in time to exhaustion and lactate utilization.

How is this new OPTYGENHP formula different than the previous formula? 

  1. This is the most-powerful OPTYGENHP forumula available.  
  2. This new formula contains two strains of Cordyceps:  Cordyceps Militaris and Cordyceps Sinensis. 
  3. This new formula no longer contains the Eleuthro extract blend.
  4. This formula is now 100% VEGAN & ALL NATURAL.  We have removed the color and it’s no longer in a bovine capsule.    

How do I use this new formula? 

You can use this new formula the same way you used the previous formulas.   For best results, use this new OPTYGEN-HP formula during all intense training. This formula will allow you to train at a higher level by improving the body’s ability to adapt to physical stress, increasing aerobic threshold and reducing lactic acid. These improvements will help you race at a higher level. For best results, OPTYGENHP should be used consistently for many months leading up to competitive events. If you start taking it a week before a race, benefits will be minimal.

Will I notice anything different vs the previous OptygenHP formula? 

The newest study on Cordyceps Militaris has been shown in a clinical study on trained cyclists to   increase VO2, improve ventilator threshold and improve time to exhaustion after three weeks of use.   Along with our Beta-Alanine, Rhodiola and OptyMax blend you should experience the following the following improvements when using this new formula vs the previous formula:




*VENTILATORY THRESHOLD refers to the point during exercise at which ventilation starts to increase at a faster rate than VO2 One's threshold is said to reflect levels of anaerobiosis and lactate accumulation. As the intensity level of the activity being performed increases, breathing becomes faster; more steadily first and then more rapid as the intensity increases. When breathing surpasses normal ventilation rate, one has reached ventilatory threshold. Comparison studies of athletic people have shown that your ventilatory threshold occurs at a higher intensity if you are more active or have been training for that exercise

Does the new formula contain ginseng? 

No, the new formula doesn’t have Eleuthero Senticosus (Ginseng), which is in the previousOPTYGENHP formula.  The new formula contains a Cordyceps extract blend instead.  The formula does still have panax notoginseng, which not a ginseng. 


Click here to download the OptygenHP research packet in Adobe Acrobat format.


Dosage recommendations: Take 4 capsules daily with a meal.

Supplement Facts
Serving Size: 4 Capsules
Amount Per Serving %DV
Chromium (as Chelavite® amino acid Chelate) 200 mcg 167%
Rhodiola Extract (Rhodiola Rosea)(root) minimum 10% rosavins 300 mg *

Cordyceps (Sinensis)(mycelia biomass) minimum 7% cordycepic acid (Militaris)(sporocarp) mimimum 10% Polysaccharides

800 mg *
Beta-Alanine 1500mg *
ActiGin Proprietary matrix (Panax notoginseng extract, Rosa Roxburghii fruit extract) 50mg *
ATProTM Matrix (Calcium Pyruvate, Sodium Phosphate, Potassium Phosphate, Ribose) 500mg *

*Daily Value Not Established

Other Ingredients: Vegan capsule

Chelavite is a registered trademark of Albion laboratories, Inc.
Covered by Albion international, Inc., U.S. Patent 5,614,553.