Clinically Proven to Improve Performance

New Formula Coming Soon

Get our new prototype formula here.

Now available in its most potent form yet. OptygenHP is clinically proven to increase VO2Max, increase the body’s ability to adapt to high levels of physical stress, increase anaerobic threshold and reduce lactic acid.

Increases VO2Max
Increases anaerobic threshold
Reduces lactic acid & Modulates Cortisol


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Increases Lactate Threshold By 42%

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Detailed Information

The Ultimate Endurance Supplement

The OptygenHP formula features our exclusive OptyMax Proprietary Matrix. Clinical studies showed a 23% improvement in endurance capacity and a significant increase in energy (ATP) production. Athletes who participated in these studies were able to replenish glycogen faster, which leads to improved recovery and improved performance on back-to-back workouts and during heavy training. In addition, subjects experienced less muscle inflammation after high-intensity exercise, resulting in less soreness and faster recovery.

This OptygenHP delivers 50% more beta-alanine. A 2012 study evaluated the effects of beta-alanine supplementation on VO2max, time to exhaustion and lactate concentrations. Subjects supplemented with beta-alanine for six weeks. The group experienced a significant increase in VO2max, an improvement in time to exhaustion and lactate utilization. The study concluded that beta-alanine supplementation can reduce lactate concentrations during exercise and thus can improve exercise performance in endurance athletes.


  1. OptygenHP is awesome Review by Christopher

    Been using this product for several seasons during peak periods. I can always feel a difference before and after as I ramp up and sharpen my training. (Posted on 11/26/2016)

  2. Effects on ability to make expeditions through high altitude jungles of the Peruvian Amazon at age of 66. Review by Gregory Deyermenjian

    For the past few years I have been regularly using OPTYGENHP, which has had great beneficial effect on my being able to continue my exploration-archaeology in the broken territory of the high-altitude jungles of Peru. To reach the exploration zones, we must first traverse the easternmost Andes mountains, on foot, and then cut our way, carrying all supplies and equipment, down into the broken territory of the unknown reaches of the upper Amazon basin. OPTYGENHP has allowed me to continue the explorations I began in 1984, when i was 35; now I am 66, and on my most recent expedition, last September, I was able to document more previously unknown ancient Incan ruins in remote territory than on any previous expedition. The ultimate in physical and mental endurance, in the ability to avoid and minimize exhaustion, and to maintain physical strength, consistently, day after day, is necessary for these investigations. (Posted on 2/7/2016)

  3. Amazing Product! Review by S Bay

    In February 2013 shortly after having my first child I had my LT tested (treadmill). I started taking OptygenHp in May after I finished nursing. With training and the use of OptygenHp my LT went from 8.5 mph (4.1 mM lactate) to 9.5 mph (4.8 mM lactate) in June of 2013. As for actual race results in my first Olympic distance triathlon of the season (June 2013) I ran a 39:14. (Posted on 3/22/2014)

  4. Not Snake Oil Review by Peyton H

    Many such products can be deemed little more than "snake oil", but Optygen HP really works. Since first implementing Optygen HP into my daily nutrition plan last winter, I have set PRs across the board, and only missed one (unscheduled) day to illness the entire year. Great product! (Posted on 1/8/2014)

  5. Amazing product Review by AAZ

    I´m a 42 y/o triathlete. Train twice daily 7 days/w . After aprox 2 weeks of use, I´ve noticed significant improvements in VO2; on muscle power and endurance; less fatigue signs during sessions; and amazing reduction in muscle soreness and recovery time. A+ product!! (Posted on 9/17/2013)

  6. Extremely Impressed!!!! Review by RMM

    Been using Optygen HP for about 3 months now, with initial expectation being very low. All I can say is this product is true to its word. Everything it claims, it delivers: recovery, energy, power, improved times with less effort, etc!!! I'm extremely impressed and I definitely would recommend!!!! Get a couple bottles and give yourself a gift!! (Posted on 9/5/2013)

  7. Good but costly Review by James

    I like the supplement and believe it has helped me recover. The "new and improved" formula may have priced me out though (20% increase). Ouch. (Posted on 7/22/2013)

  8. HP working great Review by hideano

    not ready to give it 5 stars, but so far I have noticed more energy. I want to go out and train more... recovery is definitely quicker. Remember to do the load up phase then use normally. Best to start 5-6 weeks before you big event unless you get yourself 2 bottles. (Posted on 7/21/2013)

  9. Great Product Review by TGriz

    I'm on my second bottle of the new HP. The main improvements have been in recovery times. While on the bike after hard climbs the recovery time is a lot quicker so I ride faster over all. On the flats I can push harder longer again improving my overall ride times. Also, the over night recovery is better, I don't have that "dead legs" feeling after back to back hard training days.

    One side effect that I noticed is that about 45 minutes to an hour after taking the 4 pills I get a prickly heat itch on my entire body, it lasts about 15-20 minutes before going away. It feels like my skin is itching everywhere from the inside out.

    Overall I'm very happy with the product and feel it definitely works as advertised. (Posted on 7/10/2013)

  10. BELIEVE in this product Review by Scott

    I was never really interested in all these different training aids, but after a recommendation from a friend, I tried Prototype. I have gone on to train almost daily with personal record setting results. (Posted on 5/3/2013)

  11. Definite Improvement Review by David

    Optygen HP already gave me an incredible boost in performance on the bike and I've noticed an increase in improvement after about two weeks of taking the Optygen HP prototype. I slid it right into the place of my regular Optygen HP and I've been tackling hills on my normal routes with greater ease. I'd say First Endurance has a winner here. Rip off the "Prototype" label and get this baby on the market! (Posted on 4/4/2013)

  12. Definite performance gains Review by Tommy N

    Last year I moved to altitude for the first time. I think I enjoyed some gains from my increase in efficiency, but not like this year. This year I have moved 700 metres higher, and I feel stronger and better than last year (living at 1300 metres).

    I began taking the OptygenHP Prototype in February, and after a few weeks I noticed definite performance gains. I am able to recover from hard efforts faster, and feel like I still have some more to give, even when I feel completely gassed. This is my favourite First Endurance product. (Posted on 3/26/2013)

  13. definite response Review by Phil Gaimon

    I've been training a ton, and living at altitude for the first time. I've noticed a much easier transition to the higher load on the bike than my previous experience with altitude. (Posted on 3/20/2013)

  14. Great stuff! Review by Pat Mc

    OptygenHP Prototype is the first, First Endurance product I've used and the first of any Optygen formula I've tried in training. Overall, I feel healthier and better prepared for each day's workout. I've been able to train hard and feel, overall, much less fatigued than normal. Every ride starts off great so the workout comes easier. Great stuff! (Posted on 3/20/2013)

  15. Next level Review by The Red pill

    Taking these little red pills effect isn't noticed until you start to realise that you are pushing it for longer and harder than you used to. The added of not getting sick as much and/or as for long. Fatigue from training seems less. Why would you ever stop taking them even if you are not an athlete? (Posted on 3/20/2013)

  16. They've done it again Review by Gary

    Snagged one of these bottles from a friend of mine that's sponsored. Leave it to the guys to at First Endurance to take the Optygen formula to the next level. I've been using it for 3 weeks now and bought 2 more bottles yesterday- stuff is awesome! (Posted on 3/12/2013)

  17. Great stuff Review by Gurshwin

    A Plus **** (Posted on 3/11/2013)

  18. Improvements noticed Review by PK

    After 2 weeks of using this product I noticed about 5% increase in my watts at the same heart rate effort. Testing this on 2.5mi hill repeats, and while everything else remained the same - recovery time, cadence, HR - the power was higher. (Posted on 3/11/2013)

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1.  How is this formula different than OptygenHP?  This upgraded OptygenHP formula has two key changes:

a) The amount of Beta-Alanine has been increased by 50% so there’s now 1.5 grams/serving.

b) Cordyceps has been replaced with a special proprietary matrix of Eleutherococcus senticosus extract, Panax notoginseng and Rosa Roxburghii fruit extract.  There are a number of new studies that have been done on endurance athletes that show significant endurance benefits.

2.  What should an athlete notice?  The new studies show significant improvement in various physiological and performance areas of endurance.  Athletes should notice an increased ability to handle high volume and high intensity training.  Athletes should be able to replenish glycogen faster leading to improved recovery and improved performance on back-to-back workouts and during months of heavy training.   Athletes should expect inflammatory response to high intensity exercise to improve leading to faster recovery.    The studies have proven:

-Improved glycogen re-synthesis

-Improved inflammatory response and recovery markers (less sore)

-Increase in ATP production

-Sparing of glycogen during exercise

-Improved exercise capacity

-Improved lactate curve

-Improved insulin sensitivity

 3.  What is the special OptyMax proprietary matrix?  The proprietary matrix consists of three key nutrients.  This nutrient blend is only available in the new OptygenHP product.   The blend consistes of Eleutherococcus senticosus (ES) extract, highly fractionated Panax notoginseng (PN) extract and Rosa Roxburghii (RR) fruit extract.

4.  What's the best way to us OptygenHP/Optygen?  For best results, use OptygenHP/Optygen during all intense training. Optygen will allow you to train at a higher level by improving the body’s ability to adapt to physical stress, increasing aerobic threshold and reducing lactic acid. These improvements will help you race at a higher level. For best results, OptygenHP/Optygen should be used consistently for many months. If you start taking Optygen a week before a race, benefits will be minimal.


Following exhaustive exercise, athletes fight inflammation, battle oxidative stress, need to repair torn muscle tissue, and have depleted essential glycogen stores. Glycogen is the primary storage carbohydrate in muscles and liver totaling approximately 2,000Kcal in a trained athlete. Muscle glycogen is generally known as the main fuel for strenuous sports activity. Unlike fat, this fuel can be mobilized rapidly under anaerobic condition, which typically occurs under various acute/exhaustive physical exercises.

Glycogen re-synthesis is the process of converting consumed food into stored glycogen. Even with optimal recovery after a hard workout, full glycogen re-synthesis is difficult to attain within 24 hours and subsequent workouts can begin to suffer. This is especially true when working out or racing for multiple days back to back. Having the ability to replenish glycogen to a greater degree allows athletes to bounce back from exhaustive exercise faster and be better prepared for the next day of training or racing.

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Dosage recommendations: Take 4 capsules daily with a meal.

Supplement Facts
Serving Size: 4 Capsules
Amount Per Serving%DV
Chromium (as Chelavite® amino acid Chelate) 200 mcg 167%
Rhodiola Extract (Rhodiola Rosea)(root) minimum 10% rosavins 300 mg *

OptiMax Proprietary Matrix (Eleutherococcus senticosus extract (root) minimum 0.8% eleuthrosides; Panax notoginseng extract, Rosa Roxburghii fruit extract)

850 mg *
Beta-Alanine 1500mg *
ATProTM Matrix (Calcium Pyruvate, Sodium Phosphate, Potassium Phosphate, Ribose) 500mg *

*Daily Value Not Established

Other Ingredients: gelatin red capsules

Chelavite is a registered trademark of Albion laboratories, Inc.
Covered by Albion international, Inc., U.S. Patent 5,614,553.