Seven products. One formula. The most advanced performance MVM ever.

By Luke R. Bucci, PhD CCN CNS


When we redesigned MultiV, it was better than our previous MultiV-PRO. So of course, we set out to surpass MultiV by reformulating MultiV-PRO; however, we didn’t start this process only after overhauling the standard MultiV – we’ve been doing the background research and building prototypes for three years. We weren’t going to change it unless we built something that truly deserved the “PRO” appellation. And now we have, and it’s finally ready for you.

So why push the ceiling higher – again – on an endurance-tuned MVM? After all, MultiV already covers all the vitamin and mineral gaps a dedicated, elite athlete will encounter if they’re pulling pills off the shelf. The difference is in the additional ingredients that we’ve added – and the reams and reams (and reams!) of clinical human research that support their inclusion.

To find out way more than anyone would want to know about the vitamins, minerals, and additional support technologies that constitute MultiV-PRO, check out the MultiV-PRO Research Packet, assembled and explicated by Dr. Luke Bucci.

If 100 pages of research analysis and scientific quips aren’t in your plans for the day, then Dr. Bucci has also written this more concise explanation of the ingredients, benefits, and reasons for MultiV-PRO.

New MultiV-PRO Update Is Seven Products In One!

First Endurance announces the relaunch of MultiV-PRO, an update that makes it unlike any other multivitamin/mineral – it’s actually seven (7) single products in one!

Extreme endurance exercise calls for extreme mental and physical feats over long periods of training and racing, so we developed an extreme multivitamin/mineral (MVM) that started with our already-advanced MultiV as a foundation, and then went on to build an unstoppable MVM in MultiV-PRO.

But it’s still just one bottle, so how can we say the new MultiV-PRO is seven products in one? Easily! If the label said anything other First Endurance, this product would be either a super-powerful MVM – with upgraded forms and amounts of many vitamins and minerals – or any one of six other products that are sold everywhere else as single-ingredient, stand-alone bottles with the same amount per serving as you’ll find in MultiV-PRO. 

That’s a lot. Here’s the breakdown.

  1. Comprehensive A-to-Zinc multiple vitamin/mineral tuned for elite endurance athletes.
  2. Levagen®+ with Lipisperse – enhanced absorption Palmitoylethanolamide, the regulator of your antistress Endocannabinoid System.
  3. Immulink MBG® Organic Reishi Mushroom Extract (Ganoderma lucidum) Beta Glucan for immune support
  4. Ferrochel® Iron (Ferrous bisglycinate) at a dose proven to restore iron status.
  5. Vitamin D3 (Cholecalciferol) at 100 mcg (4000 IU) per serving, more potent than most Vitamin D stand-alone products.
  6. Quatrefolic® 6S-5-L-Methyltetrahydrofolate (MTHF), the stable, bioactive form of Folate at 100% Daily Value (400 mcg DFE) that surpasses Folic Acid for Folate function.
  7. Agave Inulin, a prebiotic for gut health that is organic and non-GMO.

MultiV-PRO’s MVM Ingredients: A Firm Foundation of Essentials

In order to get the most out of MultiV-PRO’s additional, non-vitamin/mineral ingredients, your body must first be replete in all the vitamins and minerals. Both MultiV and MultiV-PRO do that well; however, MultiV-PRO has upgraded some of the forms and some of the doses – here’s the roundup for MultiV-PRO:

  • More premium nutrients are in MultiV-PRO, which means four tablets per serving – we made sure there was room for new and powerful nutrients while still providing more than enough vitamins/minerals to help your body utilize those new nutrients.
  • Vitamin D3 (Cholecalciferol) has been increased to 100 mcg per serving to help replete lower levels found in many athletes. That’s important for bone integrity stressed by intense, long-duration exercise. Vitamin D resists URTS (read: “prologue cough”) during recovery from exercise and maintains healthy muscular and vascular functions.
  • Mixed Tocopherols matching the type and amount of Vitamin E in healthy diets with antioxidant action against nitrogen-based reactive species. Unlike Vitamin E with only alpha-tocopherol, MultiV-PRO’s mixed tocopherols are balanced to work smoothly with Vitamin C and other antioxidants.
  • More Iron as Ferrochel® Ferrous bisglycinate chelate, back to 27 mg as before. Ferrochel® has been clinically tested worldwide and shown to replete Iron levels back to normal with excellent tolerance and less interference with other minerals. Since Iron drives blood cell production and oxygen use, it’s critical for endurance athletes, 70% of whom are deficient.
  • Double the amount of Choline as VitaCholine® Choline bitartrate. Choline was recently acknowledged as an essential nutrient. It’s important for brain function, DNA integrity, vitality, and even pregnancy, using L-tartaric acid sourced from wine production to help maintain blood choline levels during endurance exercise.
  • B12 goes nature-identical, changing from Cyanocobalamin to Methylcobalamin, one of the two nature-identical, active B12 forms in your body, which is necessary for red blood cell production and oxygen delivery.
  • Boron is properly chelated, changing to FruiteX-B®, a nature-identical form of chelated Boron shown to support  bone health, joint health, and energy production pathways in multiple human studies – we supply enough Boron to increase overall daily intake into the healthiest range.
  • More Chromium, increased to 400 mcg per serving, matching the type and doses used in human clinical studies that show preservation of lean body mass.
  • More minerals in 100% chelated forms, bringing equal or greater uptake with a lower label amount. Chelated means better absorption, less interactions with other nutrients, and better tolerability. Magnesium and zinc are the minerals that benefit most from being 100% chelated, since their bioavailability tends to be inhibited by fiber, calcium, iron and phosphates in the diet.

MultiV-PRO’s Additional Ingredients: Powerful, Specific Upgrades

  • GI Tract Support – Microbiomes in athletes are becoming more important to maintain overall health, performance and recovery, so we added a clinically studied dose of Inulin (from Agave roots) to specifically help your microbiome help you. Also, Beta Glucan from Reishi mushrooms (mycelia), Green Tea and Ginkgo biloba extracts, and double the amount of Spectra® Total ORAC5 blend (also mostly polyphenols), also have positive actions on human microbiomes reported in human studies.
  • Increased Immune Support from the clinically studied dose of Super Beta Glucan from Immulink MBG® Organic Reishi Mushroom Extract. Reishi Beta Glucans are more complicated than yeast Beta Glucans and have additional actions to support your immune system.
  • The Game-Changing Antidote for Exercise Stress. Levagen®+ is the much-easier-to-pronounce tradename for Palmitoylethanolamine (PEA). As Levagen®+, PEA is combined with Lipsperse® to increase uptake, helping to keep pill size manageable. Your body makes PEA to coordinate your repair and adaptive systems’ responses to physical stress – especially intense exercise! One way PEA manifests is the Runner’s High endurance athletes of all types experience during exercise.

Vitamins, Minerals, and Additional Ingredients: What Stayed the Same

  • Vitamin A as Beta-Carotene, which provides immune support and antioxidant activity that doesn’t impede recovery.
  • Vitamin K (as K1 & K2 MK7), which boosts max heart output; reinforces blood vessel, bone, and joint health; supports reduced cramping and backing energy production.
  • Vitamin B1 as Thiamin, a critical component of enzymes that drive ATP production.
  • Vitamin B2 as Riboflavin, which helps produce energy and metabolize fat.
  • Vitamin B3, Niacin as Niacinamide, which adds to the energy production processes and supports synthesis of fat-soluble compounds and antioxidant functions.
  • Vitamin B6, which helps metabolize protein and amino acids and is vital for blood cell and hemoglobin production.
  • Vitamin C, which supports recovery and immune functions.
  • Zinc, which touches all the basic metabolic and immune functions.
  • Folate, which supports blood cell formation and cardiovascular health.
  • Biotin, which supports insulin signaling and using glucose, fatty acids, and amino acids for ATP production.
  • Pantothenic Acid, which ushers carbs, fats, and proteins into the energy production pathways.
  • Calcium, prevents muscle cramps, transports cellular compounds, and is essential for nervous and cardiovascular functions.
  • trace and ultratrace minerals/elements
  • Iodine, a component of thyroid hormones that supports metabolic functions.
  • Selenium, an antioxidant supersoldier that also supports immune and thyroid functions.
  • Magnesium, which improves endurance performance, supports energy production, and is a critical – though often overlooked – electrolyte for preventing cramps.
  • Manganese, which supports amino acid and energy metabolism with an added dose of help for your bones and joints.
  • Molybdenum, which helps manage waste produced by ATP degradation and prevents sulfite sensitivity.
  • Copper is changed to Bisglycinate chelate in MultiV-PRO. It supports immune function, blood cell production, and connective tissues – plus multiple metabolic functions.
  • Spectra® Total ORAC5, and antioxidant blend that doesn’t interfere with recovery functions.
  • Green tea, which provides antioxidant and immune support and promotes fat burning for ketone formation.
  • Ginkgo biloba extracts, which is clinically tested to improve VO2 max and altitude adaptation.

MultiV-PRO Overview Summary

Advances in nutrition science for vitamins and minerals. Newly revamped additional ingredients to improve Health, Wellness, Energy, and Performance. Maximized effects by combining sufficient vitamins and minerals with specific nutrients in forms and amounts specifically chosen for intense endurance athletes like you. Seven supplements in one.

There is nothing like MultiV-PRO.

October 19, 2023 — Luke Bucci
Tags: news research

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